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Despite their shared origin, Melanotan II and PT-141 differ significantly in their receptor selectivity, physiological effects, intended research focus, and safety considerations

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LPO staining results exhibited a higher LPO accumulation in the ZFPG group than the ZFP group, indicating that the multienzyme activities of ZFPG NPs amplified the LPO accumulation, thereby inducing robust ferroptosis of cancer cells (Fig