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Indirect Side Effects That Affect Skin Appearance Some of the common side effects of NAD+ shots are nausea, fatigue, or headaches

Theres also the possibility of increased cortisol levels, which can mess with your mood and energy if they get out of whack, Calvert says

The medication is administered as a once-weekly subcutaneous injection, with doses ranging from 2.5 mg to 15 mg depending on the indication and individual tolerance