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4 Discussion AFT is the most hazardous toxin that frequently contaminates grains, food, and feedstuff and remains after food processing, raising serious health concerns ( Ample literature, including our and others preceding studies, strongly indicate that excess oxidant production and cellular antioxidant depletion are fundamental pathways embroiled in AFT-induced nephrotoxicity ( 2 ), hydroxyl radicals (OH ), and hydrogen peroxide (H 2 O 2 )

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doi: 10.3233/JAD-160152 179 IwaiY.ShibuyaK.MisawaS.SekiguchiY.WatanabeK.AminoH.et al

Specifically, pernicious anemia is anemia caused by a deficiency of vitamin B12 due to a lack of absorption