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Common causes include: Pernicious anaemia Conditions affecting absorption in the stomach or intestines Certain medications Dietary insufficiency, particularly in strict vegan diets Increasing age Identifying the underlying cause is important because treatment recommendations may vary

Allow the peptide to dissolve naturally by gently swirling, never shaking, the vial

One unit equals one injection of one drug or substance

The mechanisms behind B12 deficiency in metformin users are multifactorial but are probably related to intestinal absorption, so it seems sensible to assume that oral B12 replacement may be less effective, although there is little evidence in this area