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cGAS/STING pathway in microglial diseases In the context of neurodegeneration, amplification of microglial cGAS-STING signaling, along with IFN production and cGAS-driven senescence, has been implicated as a disease-promoting mechanism in female mice ( R47H variant, indicating both associated with increased risk and earlier onset of Alzheimer's disease and their potential role as upstream modulators of AD pathogenesis (Yu et al., 2020)

Dermal T cells, recognized for their high-level production of IL-17, are of great significance in the progression of psoriasis [206, 207]

[DOI] [PubMed] [Google Scholar] 97.Verbraecken J, Declerck A, Van De Heyning P, De Backer W, Wouters EFM

When you eat foods with high levels of fat, the excess fat is stored in the body