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In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]

At the time, nothing on his box of Extra Strength Tylenol warned about the risk of drinking or liver damage

The reaction was stopped by adding EDTA (5 mM) at the indicated times