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In a pooled analysis of the two monotherapy studies, the add-on to metformin study, and the add-on to pioglitazone study, the incidence of selected gastrointestinal adverse reactions in patients treated with JANUVIA was as follows: abdominal pain (JANUVIA 100 mg, 2.3%
There was a trend for higher numbers of baseline comorbidities being associated with a higher CVD risk score, suggesting that the 27-protein score quantifies relative CVD risk in the STEP 1 cohort (Fig
Nociti V, Romozzi M
It was first isolated from the unripe berries of the Sorbus aucuparia -rowan tree-, hence its name
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