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Though the exact way semaglutide causes weight loss is unknown, the above changes appear to impact weight loss positively

GLP-1, the endogenous agonist of GLP-1R, is predominantly synthesized in enteroendocrine cells of the distal small intestine and secreted in the blood when food enters the duodenum [4, 5]

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Key sources include: Red meat such as beef, lamb, and pork Poultry including chicken and turkey Fish like cod, salmon, and tuna Dairy products such as milk, cheese, and yogurt Plant-based sources including avocados, soybeans, and tempeh Because plant sources contain much lower amounts of L-carnitine, vegetarians and vegans may struggle to obtain sufficient levels through diet alone