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Gastroenterology 2011;141:150156

These inconsistent results also translate to human studies where obesity and steatosis correlated with increased hepatotoxicity after an APAP overdose in some studies [181] and no correlation of toxicity with obesity was observed in other studies [182]

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[5] [6] The bioavailability of levothyroxine ranges from 4080% and can be reduced by numerous factors including food (particularly high-fibre foods, soya products, and coffee), medications (especially those affecting gastric pH), and supplements containing calcium, iron, or magnesium