doi: 10.1186/s13098-017-0254-9
The NHS Digital Weight Management Programme typically requires a BMI 30 kg/m (or 27.5 kg/m for certain ethnic groups) plus additional risk factors such as diabetes or hypertension
Effects: By activating GLP-1 receptors, Tirzepatide increases insulin secretion in response to meals, reduces glucagon release (which helps lower blood sugar), and slows gastric emptying (promoting feelings of fullness)
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