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Retrieved July 30, 2015

When constructing these lineages, we only used differentiating basal, secretory, and ciliating/ciliated populations, where lineages were constrained to begin with the differentiating basal population and to end with either the mature secretory (secretory cell 2) or mature ciliated populations

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Sample size calculation The required sample size was estimated to be 363 (min 272) based on the prevalence of IBS in the general population being estimated to be 13% with an estimated error of 4%, Type 1 error (alpha) 5% (two-tailed), power 95%, and allowing for a 25% dropout rate